an update in daly city, northbound 280 near the geneva observation avenue exit with the accident cleared on 280. we will look at the mass transit options if you traveling from the central valley where it is slow on 5th. >> breaking news from the live desk. >> a huge explosion at factory in brazil the financial center. an image from twitter put out by the country's largest news outlet. they are reporting it is a they are reporting it is a mattress factory with no word on of fuel because if it is mattresses in the factory we have huge flumes, a lost flames reported. numerous cruise are on battling this. smoke and flames can be seen for miles. i will keep an eye out for information as we get word on injuries. new at 6:00, a big breakthrough that could become the cure for h.i.v. infections around the world. >> troubling numbers on package thefts. how they are changing the behavior of a lost shoppers. >> newly wed couple town as traffic jam into a moment to remember. we will take >> quick break. stay tuned. ...one of many pieces in my i havlife.hma... so when my asthma symptoms kept coming ba